Anti-GBM Disease in Pregnancy

Autor: Mohammed Muqeet Adnan MD, Jordan Morton MD, Syed Hashmi MD, Sufyan Abdul Mujeeb DO, William Kern MD, Benjamin D. Cowley MD
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Investigative Medicine High Impact Case Reports, Vol 4 (2015)
Druh dokumentu: article
ISSN: 2324-7096
23247096
DOI: 10.1177/2324709615624232
Popis: Antiglomerular basement membrane (GBM) disease presenting during pregnancy is uncommon. We present a case of a pregnant female who presented with acute renal failure requiring dialysis due to anti-GBM disease. She responded well to plasma exchange, high-dose steroids, and hemodialysis. Cyclophosphamide was discussed but not given at the patient’s request due to concerns for the well-being of the fetus. Unfortunately, she suffered a spontaneous abortion in her eighth week of pregnancy. Subsequently, she had progressive improvement in her renal function and became hemodialysis independent at 2 weeks after diagnosis. Her renal function returned to baseline 3 months after diagnosis. We present this case in detail and review the literature regarding anti-GBM disease in pregnancy.
Databáze: Directory of Open Access Journals