Anti-GBM Disease in Pregnancy
Autor: | Mohammed Muqeet Adnan MD, Jordan Morton MD, Syed Hashmi MD, Sufyan Abdul Mujeeb DO, William Kern MD, Benjamin D. Cowley MD |
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Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: | |
Zdroj: | Journal of Investigative Medicine High Impact Case Reports, Vol 4 (2015) |
Druh dokumentu: | article |
ISSN: | 2324-7096 23247096 |
DOI: | 10.1177/2324709615624232 |
Popis: | Antiglomerular basement membrane (GBM) disease presenting during pregnancy is uncommon. We present a case of a pregnant female who presented with acute renal failure requiring dialysis due to anti-GBM disease. She responded well to plasma exchange, high-dose steroids, and hemodialysis. Cyclophosphamide was discussed but not given at the patient’s request due to concerns for the well-being of the fetus. Unfortunately, she suffered a spontaneous abortion in her eighth week of pregnancy. Subsequently, she had progressive improvement in her renal function and became hemodialysis independent at 2 weeks after diagnosis. Her renal function returned to baseline 3 months after diagnosis. We present this case in detail and review the literature regarding anti-GBM disease in pregnancy. |
Databáze: | Directory of Open Access Journals |
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