Stability of Differently Modified Lutein Nanostructured Lipid Carriers During Colonic Digestion and Their Interaction with Feces Microbiota

Autor: Xiaoqin WANG, Hongxu YAN, Yayuan XU, Dajing LI, Yihong BAO, Zhuqing DAI
Jazyk: čínština
Rok vydání: 2024
Předmět:
Zdroj: Shipin gongye ke-ji, Vol 45, Iss 16, Pp 376-383 (2024)
Druh dokumentu: article
ISSN: 1002-0306
DOI: 10.13386/j.issn1002-0306.2023090276
Popis: To prepare different types of lutein nanostructured lipid carriers (LNLs) using chitosan (CS), chitosan-epigallocatechin gallate covalent (C-CS-EGCG), and chitosan-epigallocatechin gallate ester non-covalent (Non-C-CS-EGCG) modifications combined with high-pressure microfluidization. A simulated colonic digestion model was established to investigate the stability and interaction with gut microbiota of these modified lutein nanostructured lipid carriers. Results showed that after 24 hours of simulated in vitro colonic fermentation, the lutein content in CS-LNLs significantly decreased (P
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