Epidemiology of hyperkalemia in chronic kidney disease

Autor: Lara Belmar Vega, Emilio Rodrigo Galabia, Jairo Bada da Silva, Marta Bentanachs González, Gema Fernández Fresnedo, Celestino Piñera Haces, Rosa Palomar Fontanet, Juan Carlos Ruiz San Millán, Ángel Luis Martín de Francisco
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nefrología (English Edition), Vol 39, Iss 3, Pp 277-286 (2019)
Druh dokumentu: article
ISSN: 2013-2514
DOI: 10.1016/j.nefroe.2018.11.014
Popis: Background: Hyperkalaemia is a significant electrolyte imbalance in chronic kidney disease (CKD). Renin–angiotensin–aldosterone system inhibitors (RAASi) have beneficial cardio-renal properties, although they can often cause hyperkalaemia. Objective: To examine the prevalence of hyperkalaemia in CKD, identify factors associated with its appearance and the relationship between hyperkalaemia and mortality. Patients and methods: Retrospective observational study on patients with CKD in the period 1971–2017. The population was categorised into 3 groups: Group 1, patients with CKD without renal replacement therapy; Group 2, patients on haemodialysis; and Group 3, patients on continuous ambulatory peritoneal dialysis. Results: A total of 2629 patients were evaluated. The prevalence observed in the different groups was: 9.6%, 16.4% and 10.6%, respectively. Risk factors related to the appearance of hyperkalaemia in the CKD group were glomerular filtration rate (GFR) (p
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