Assessment of Indices of Vascular Involvement in Children with Idiopathic Nephrotic Syndrome: A Case-control Study
Autor: | Alok khanna, Mukesh saini, Ashuma sachdeva, Jyotsna sen, kapil bhalla, Animesh debbarma, Yogesh verma, Preet lamba |
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Jazyk: | angličtina |
Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Journal of Clinical and Diagnostic Research, Vol 17, Iss 10, Pp 15-19 (2023) |
Druh dokumentu: | article |
ISSN: | 2249-782X 0973-709X |
DOI: | 10.7860/JCDR/2023/64029.18607 |
Popis: | Introduction: Nephrotic Syndrome (NS) is characterised by proteinuria, oedema, hypoalbuminaemia, and hypercholesterolemia. The latter is a risk factor for atherosclerosis, suggesting a higher risk of cardiovascular disease in children with NS. Atherosclerosis is proposed to be caused by vascular endothelial dysfunction, reflecting the inflammatory response to tissue damage. Aim: To investigate indices of early vascular involvement in children with Idiopathic Nephrotic Syndrome (INS). Materials and Methods: This case-control study was conducted at a tertiary-care hospital, Pt. BD Sharma PGIMS Rohtak, Haryana, India, over a period of two years and two months. The study included 50 children aged |
Databáze: | Directory of Open Access Journals |
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