Integration of drug safety monitoring in tuberculosis treatment programmes: country experiences
| Autor: | Edine Tiemersma, Susan van den Hof, Gunta Dravniece, Fraser Wares, Yohannes Molla, Yusie Permata, Endang Lukitosari, Mamel Quelapio, Si Thu Aung, Khay Mar Aung, Hoang Thanh Thuy, Vu Dinh Hoa, Merkinai Sulaimanova, Saadat Sagyndikova, Mavluda Makhmudova, Alijon Soliev, Michael Kimerling |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | European Respiratory Review, Vol 28, Iss 153 (2019) |
| Druh dokumentu: | article |
| ISSN: | 0905-9180 1600-0617 16000617 |
| DOI: | 10.1183/16000617.0115-2018 |
| Popis: | New drugs and shorter treatments for drug-resistant tuberculosis (DR-TB) have become available in recent years and active pharmacovigilance (PV) is recommended by the World Health Organization (WHO) at least during the early phases of implementation, with active drug safety monitoring and management (aDSM) proposed for this. We conducted a literature review of papers reporting on aDSM. Up to 18 April, 2019, results have only been published from one national aDSM programme. Because aDSM is being introduced in many low- and middle-income countries, we also report experiences in introducing it into DR-TB treatment programmes, targeting the reporting of a restricted set of adverse events (AEs) as per WHO-recommended aDSM principles for the period 2014–2017. Early beneficial effects of active PV for TB patients include increased awareness about the occurrence, detection and management of AEs during TB treatment, and the increase of spontaneous reporting in some countries. However, because PV capacity is low in most countries and collaboration between national TB programmes and national PV centres remains weak, parallel and coordinated co-development of the capacities of both TB programmes and PV centres is needed. |
| Databáze: | Directory of Open Access Journals |
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