| Autor: |
Didier Lustermans, Roua Abdulrahim, Vicki Trier Taasti, Juliane Szkitsak, Evita Švėgždaitė, Sarina Clarkin, Brigitte Reniers, Frank Verhaegen, Gabriel Paiva Fonseca |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Physics and Imaging in Radiation Oncology, Vol 32, Iss , Pp 100656- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2405-6316 |
| DOI: |
10.1016/j.phro.2024.100656 |
| Popis: |
Background and purpose: In radiotherapy, the image quality of four-dimensional computed tomography (4DCT) is often degraded by artifacts resulting from breathing irregularities. Quality assurance mostly employ simplistic phantoms, not fully representing complexities and dynamics in patients. 3D-printing allows for design of highly customized phantoms. This study aims to validate the proof-of-concept of a realistic dynamic thorax phantom and its 4DCT application. Materials and methods: Using 3D-printing, a realistic thorax phantom was produced with tissue-equivalent materials for soft tissue, bone, and compressible lungs, including bronchi and tumors. Lung compression was facilitated by motors simulating customized breathing curves with an added platform for application of monitoring systems. The phantom contained three tumors which were assessed in terms of tumor motion amplitude. Three 4DCT sequences and repeated static images for different lung compression levels were acquired to evaluate the reproducibility. Moreover, more complex patient-specific breathing patterns with irregularities were simulated. Results: The phantom showed a reproducibility of ±0.2 mm and ±0.4 mm in all directions for static 3DCT images and 4DCT images, respectively. Furthermore, the tumor close to the diaphragm showed higher amplitudes in the inferior/superior direction (13.9 mm) than lesions higher in the lungs (8.1 mm) as observed in patients. The more complex breathing patterns demonstrated commonly seen 4DCT artifacts. Conclusion: This study developed a dynamic 3D-printed thorax phantom, which simulated customized breathing patterns. The phantom represented a realistic anatomy and 4DCT scanning of it could create realistic artifacts, making it beneficial for 4DCT quality assurance or protocol optimization. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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