| Autor: |
Li Zhang, Yuanbin Li, Honglei Wang, Yirui Guo, Xiaotong Wang, Hongmei Wu, Qing Zhang, Li Liu, Ge Meng, Shunming Zhang, Shaomei Sun, Ming Zhou, Qiyu Jia, Kun Song, Anna Stubbendorff, Yeqing Gu, Kaijun Niu |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
BMC Immunology, Vol 25, Iss 1, Pp 1-9 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2172 |
| DOI: |
10.1186/s12865-024-00637-9 |
| Popis: |
Abstract Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by hyperglycemia resulting from defects in insulin secretion and/or insulin action. Increasing evidence suggests that inflammation played an important role in the pathogenesis of T2DM. Prospective studies on the link between immunoglobulins concentrations and the risk of T2DM in adults are limited. We developed a cohort study including 7,093 adults without T2DM history. The incidence of T2DM was 16.45 per 1,000 person-years. Compared with the lowest quartiles, the hazard ratios (95% confidence intervals) of T2DM for the highest quartiles of IgG, IgE, IgM and IgA were 0.64 (0.48–0.85), 0.94 (0.72–1.23), 0.68 (0.50–0.92) and 1.62 (1.24–2.11) (P for trend was |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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