A Comparative Study of Architecture and Quality of Sleep among Juvenile Myoclonic Epilepsy Patients and Healthy Individuals Attending Tertiary Care Hospital in Central India

Autor: Ashwin Lathiya, Dilip Maheshwari, Bharat Bhushan, Vijay Sardana, Vaibhav Somvanshi, Shubham Garg, Vinod Singh Jatav
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Sleep Sciences, Vol 7, Iss 3-4 (2024)
Druh dokumentu: article
ISSN: 2476-2938
2476-2946
DOI: 10.18502/jss.v7i(3-4).15248
Popis: Background and Objective: Primary sleep disorders are common in patients with epilepsy. Seizures, epileptiform discharges, and antiepileptic drugs alter the sleep architecture of patients with juvenile myoclonic epilepsy (JME). We evaluated sleep architecture and its quality in these patients. Materials and Methods: Thirty patients with JME (11 men and 19 women with mean age of 21.10 ± 4.55 years) and 30 healthy controls underwent overnight polysomnography (PSG). Sleep quality and daytime sleepiness were assessed using Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS), respectively. Results: Myoclonus and generalized tonic-clonic seizures (GTCS) were present in all patients with JME, while absence seizures were in 13.3%. Sleep deprivation was the most frequent precipitating factor for seizures (56.6%) followed by fatigue, sound, and photic stimulation. Patients with JME reported a statistically significant drop in sleep efficiency (P
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