An efficient method for the synthesis of substituted N-aryl lactams
| Autor: | Devdutt Chaturvedi, Amit K. Chaturvedi, Pragyandip P. Dash, Nisha Mishra |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Current Chemistry Letters, Vol 4, Iss 3, Pp 119-126 (2015) |
| Druh dokumentu: | article |
| ISSN: | 1927-7296 1927-730X |
| DOI: | 10.5267/j.ccl.2015.3.005 |
| Popis: | A quick, efficient, and one-pot method for the synthesis of substituted N-aryl lactams through the reaction of various kinds of corresponding substituted arenes with a variety of ω-azido alkanoic acids using trifluoromethanesulfonic acid (triflic acid) at room temperature, by in-situ involvement of Friedel-Crafts reaction followed by intramolecular Schmidt rearrangement was developed, and afforded good to excellent yields. |
| Databáze: | Directory of Open Access Journals |
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