Autor: |
Karamjit Singh Dolt, Melanie L Lawrence, Eve Miller-Hodges, Joan Slight, Anna Thornburn, Paul S Devenney, Peter Hohenstein |
Jazyk: |
angličtina |
Rok vydání: |
2013 |
Předmět: |
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Zdroj: |
PLoS ONE, Vol 8, Iss 4, p e62054 (2013) |
Druh dokumentu: |
article |
ISSN: |
1932-6203 |
DOI: |
10.1371/journal.pone.0062054 |
Popis: |
There is an increasing need for more efficient generation of transgenic constructs. Here we present a universal multi-site Gateway vector for use in recombineering reactions. Using transgenic mouse models, we show its use for the generation of BAC transgenics and targeting vectors. The modular nature of the vector allows for rapid modification of constructs to generate different versions of the same construct. As such it will help streamline the generation of series of related transgenic models. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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