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Introduction: Myrica rubra (M. rubra) is a subtropical fruit tree that is indigenous to China and other Asian nations. Chinese history contains references to this Myricaceae plant dating back more than 2000 years. The fruit is delicious with attractive colour, flavour and high economic value. Traditional Chinese medicine (TCM) utilised it in the treatment of mouth and gums related problems, cold, flu asthma and laryngitis. Research efforts suggested bayberry extract found to have antioxidant that exhibit bioactivities counteracting allergens, inflammation, diabetes, bacterial infection and other health issues. Methodology: The online database including Google Scholar, Scopus, PubMed, and Web of Science were searched using different keywords: M. rubra phytochemistry, pharmacology and toxicology. The purpose of this review was therefore to summarize the previously reported phytochemicals, pharmacological status of the chosen Chinese plant species. Results: Our research demonstrates that M. rubra contains a variety of chemical compounds that are physiologically active, including flavonoids and terpenoids. Furthermore, previous studies have demonstrated the significant pharmacological action of M. rubra plant extracts and derived principles, including their anti-tumor, anti-inflammatory, antioxidant, and anti-aging capabilities. Discussion: The research cited below indicates that M. rubra has a significant potential for the development of drugs and dietary supplements for the prevention and treatment of cancer, ulcer, diabetes, and other disorders. Chinese bayberry (CB) should be incorporated in dietary intakes as well as active ingredients in pharmaceutical formulations because clinical research has further shown that it is safe and effective for human consumption. Conclusion: M. rubra is a rich source of bioactive substances that can be added to human food and have the potential to treat mild to serious medical disorders. This evaluation will motivate additional investigation into the chosen plant species by other researchers, especially in the areas of toxicity and bioactivity. |