| Autor: |
Mónica R. Meza-Meza, José Francisco Muñoz-Valle, Adolfo I. Ruiz-Ballesteros, Barbara Vizmanos-Lamotte, Isela Parra-Rojas, Erika Martínez-López, Edith Oregon-Romero, Yolanda Fabiola Márquez-Sandoval, Sergio Cerpa-Cruz, Ulises de la Cruz-Mosso |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Journal of Immunology Research, Vol 2021 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2314-7156 |
| DOI: |
10.1155/2021/2808613 |
| Popis: |
Vitamin D (calcidiol) deficiency in systemic lupus erythematosus (SLE) is more frequent than in healthy subjects (HS); it is associated with clinical activity and damage in SLE. Although calcidiol is considered the best indicator of the vitamin D serum status, its deficiency could not reflect its hydroxylation efficiency ratio and calcitriol serum status. This study was aimed at assessing the association of calcidiol and calcitriol serum levels and its hydroxylation efficiency ratio with the risk to clinical and renal disease activities in SLE patients. A cross-sectional study was conducted in 308 SLE and HS women; calcidiol and calcitriol serum levels were evaluated by immunoassays. SLE patients showed lower calcidiol serum levels vs. HS (21.2 vs. 24.2 ng/mL; p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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