COMBINED LIVER-PANCREAS TRANSPLANTATION: THE FIRST RUSSIAN EXPERIENCE

Autor: S. V. Gautier, O. M. Tsirulnikova, V. N. Poptsov, S. V. Arzumanov, I. V. Pogrebnichenko, A. A. Ammosov, Y. E. Lurie, N. S. Muratova, N. V. Gamgiya, H. M. Hizroev, S. V. Fokin, V. V. Pchelnikov
Jazyk: ruština
Rok vydání: 2010
Předmět:
Zdroj: Vestnik Transplantologii i Iskusstvennyh Organov, Vol 12, Iss 4, Pp 27-32 (2010)
Druh dokumentu: article
ISSN: 1995-1191
DOI: 10.15825/1995-1191-2010-4-27-32
Popis: Combined liver-pancreas transplantation is considered to be a reasonable treatment of patients with end-stage liver disease and concomitant insulin-dependent diabetes mellitus, so it may become a standard treatment of this category of patients. As known, diabetes mellitus negatively affects the long-term results of isolated liver transplantation and increases a risk of posttransplant complications. Notwithstanding the widening range of indi- cations for simultaneous liver-pancreas transplantation and advances of transplantology, this operation continues to be a rare event in world medical practice. In May 2010 in Academician V.I. Shumakov Federal Research Cen- ter of Transplantology and Artificial Organs there was performed a first in Russia simultaneous liver-pancreas transplantation to 17-years old recipient, suffering with liver cirrhosis (as a result of autoimmune hepatitis) and concomitant insulin-dependent diabetes mellitus. In this article we give an overview of indications for simultaneous liver-pancreas transplantation, different ope- rative techniques, immunological aspects and immunosuppression regimes, as well as we describe the first in Russian experience of such transplantation.
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