Acute Low-Dose Hyperoxia during a Single Bout of High-Intensity Interval Exercise Does Not Affect Red Blood Cell Deformability and Muscle Oxygenation in Trained Men—A Randomized Crossover Study

Autor: Nils Freitag, Tim Böttrich, Pia D. Weber, Giorgio Manferdelli, Daniel A. Bizjak, Marijke Grau, Tanja C. Sanders, Wilhelm Bloch, Moritz Schumann
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Sports, Vol 8, Iss 1, p 4 (2020)
Druh dokumentu: article
ISSN: 2075-4663
DOI: 10.3390/sports8010004
Popis: Recent technological developments provide easy access to use an artificial oxygen supply (hyperoxia) during exercise training. The aim of this study was to assess the efficacy of a commercially available oxygen compressor inducing low-dose hyperoxia, on limiting factors of endurance performance. Thirteen active men (age 24 ± 3 years) performed a high-intensity interval exercise (HIIE) session (5 × 3 min at 80% of Wmax, separated by 2 min at 40% Wmax) on a cycle ergometer, both in hyperoxia (4 L∙min−1, 94% O2, HYP) or ambient conditions (21% O2, NORM) in randomized order. The primary outcome was defined as red blood cell deformability (RBC-D), while our secondary interest included changes in muscle oxygenation. RBC-D was expressed by the ratio of shear stress at half-maximal deformation (SS1/2) and maximal deformability (EImax) and muscle oxygenation of the rectus femoris muscle was assessed by near-infrared spectroscopy. No statistically significant changes occurred in SS1/2 and EImax in either condition. The ratio of SS1/2 to EImax statistically decreased in NORM (p < 0.01; Δ: −0.10; 95%CI: −0.22, 0.02) but not HYP (p > 0.05; Δ: −0.16; 95%CI: −0.23, −0.08). Muscle oxygenation remained unchanged. This study showed that low-dose hyperoxia during HIIE using a commercially available device with a flow rate of only 4 L·min−1 may not be sufficient to induce acute ergogenic effects compared to normoxic conditions.
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