| Autor: |
Ann Prasad Mary, Hanumanthappa Nandeesha, Dasari Papa, Thyagaraju Chitra, Rajesh Nachiappa Ganesh, Vikas Menon |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
International Journal of Reproductive BioMedicine, Vol 19, Pp 333-338 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2476-3772 |
| DOI: |
10.18502/ijrm.v19i4.9059 |
| Popis: |
Background: Matrix metalloproteinase-9 (MMP-9), interleukin-17 (IL-17) and psychological stress are known to play a role in the pathogenesis of male infertility. Objective: To assess the association of MMP-9 with IL-17 and psychological stress in infertile men. Materials and Methods: In this cross-sectional study, 39 men with infertility diagnosed based on semen analysis and 39 subjects with normal semen analysis were included in the study. MMP-9 and IL-17 were estimated in both groups by ELISA. Perceived stress scale was used to assess psychological stress in controls and cases. Results: In infertile cases, MMP-9 and IL-17 were significantly increased when compared with controls (p = 0.046, p = 0.041 respectively). A significant association of MMP-9 was observed with IL-17 (r = 0.335, p = 0.037) and perceived stress scale (r = 0.329, p = 0.041). Conclusion: IL-17 and stress increase MMP- 9 levels in infertile men. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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