Improved anorgasmia following add-on lamotrigine treatment

Autor: Seyede Maryam Naghibi, Seyed Hamzeh Hosseini
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Trends in Pharmaceutical Sciences, Vol 9, Iss 4, Pp 239-242 (2023)
Druh dokumentu: article
ISSN: 2423-5652
DOI: 10.30476/tips.2023.99953.1211
Popis: Sexual dysfunction is common after using antiepileptic drugs, and anorgasmia can occur as a treatment-emergent adverse event. The positive effect of lamotrigine on improving anorgasmia in epilepsy patients has been reported in a few studies. Anorgasmia is a common manifestation in epileptic patients. Anorgasmia or ejaculation without achieving orgasm is permanent or recurrent, happening despite adequate stimulation. The current paper presented a 31-year-old male with epilepsy since early childhood who received carbamazepine and phenobarbital. He experienced anorgasmia, and by switching to valproate sodium, the seizures and anorgasmia were somewhat improved. However, both problems were completely resolved after receiving lamotrigine. An 18-month follow-up did not reveal any particular issue. Lamotrigine can be recommended alongside other antiepileptic drugs in patients who have cure-induced anorgasmia. Considering the improvement of anorgasmia and reduced number of seizures, long-term follow-up is recommended.
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