Liver Graft-to-Spleen Volume Ratio as a Useful Predictive Factor of the Outcomes in Living Donor Liver Transplantation: A Retrospective Study

Autor: Fei Xiao, Lin Wei, Wei Qu, Zhi-Gui Zeng, Li-Ying Sun, Ying Liu, Hai-Ming Zhang, Yu-Le Tan, Jun Wang, Zhi-Jun Zhu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Frontiers in Surgery, Vol 9 (2022)
Druh dokumentu: article
ISSN: 2296-875X
DOI: 10.3389/fsurg.2022.855695
Popis: BackgroundIn living donor liver transplantation (LDLT), graft-to-recipient weight ratio (GRWR) 1.03 g/mL). For the donors, there were significant differences in donor age, graft type, liver size, GRWR, and GSVR (P < 0.05). Following the surgical factors, there were significant differences in blood loss and CRBC transfusion (P < 0.05). The low GSVR has demonstrated had a significant relationship with ascites drainage and portal venous flow after LDLT (P < 0.05). Meanwhile, low GSVR heralds worse results which covered platelet count, international normalized ratio (INR), and portal venous velocity. Kaplan–Meier analysis showed that there was a significant difference between the two groups, while the low GSVR group demonstrated worse recipients survival compared with the normal GSVR group (P < 0.05).ConclusionsWithout splenectomy, low GSVR was an important predictor of portal hypertension and impaired graft function after LDLT.
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