Development of Eosinophilia in dogs intradermically inoculated with sand fly saliva and Leishmania (Leishmania) chagasi stationary-phase promastigotes

Autor:	Moacir Paranhos, Washington C. dos Santos, Italo Sherlock, Geraldo G. S. Oliveira, Lain C. Pontes de Carvalho
Jazyk:	angličtina
Rok vydání:	1993
Předmět:	Leishmania chagasi Lutzomia longipalpis sand fly saliva eosinophilia infectivity experimental infection dogs Microbiology QR1-502 Infectious and parasitic diseases RC109-216
Zdroj:	Memorias do Instituto Oswaldo Cruz, Vol 88, Iss 2, Pp 249-251 (1993)
Druh dokumentu:	article
ISSN:	0074-0276 1678-8060
DOI:	10.1590/S0074-02761993000200012
Popis:	Salivary glad lysates of the sand fly Lutzomia longipalpis have been shown to enhance the infectivity of Leishmania in mice. As shown herein, the simultaneous inoculation of Leishmania chagasi stationary-phase promastigotes and L. longipalpis salivary gland by the intradermal route in a group of mongrel dogs induced a statistically significant eosinophilia, in relation to dogs inoculated with Leishmania or with salivary gland lysate only. These dogs had no evidence of infection, in spite of the infectivity of the promastigotes when inoculated by the intravenous route.
Databáze:	Directory of Open Access Journals
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