Phase separation driven by interchangeable properties in the intrinsically disordered regions of protein paralogs

Autor: Shih-Hui Chiu, Wen-Lin Ho, Yung-Chen Sun, Jean-Cheng Kuo, Jie-rong Huang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-022-03354-4
Popis: A comparison of structure-function relationship for intrinsically disordered regions (IDRs) among paralogs shows that differences in physicochemical properties of the IDR between paralogs are compensated for to converge on the same biophysical function.
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje