An Overview of the Biological Activity of Pyrrolo[3,4-c]pyridine Derivatives

Autor:	Anna Wójcicka, Aleksandra Redzicka
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	pyrrolo[3 4-c]pyridine pyrrole heterocycles biological activity structure-activity relationships analgesic activity azaizoindoles Medicine Pharmacy and materia medica RS1-441
Zdroj:	Pharmaceuticals, Vol 14, Iss 4, p 354 (2021)
Druh dokumentu:	article
ISSN:	1424-8247
DOI:	10.3390/ph14040354
Popis:	Pyrrolo[3,4-c]pyridine is one of the six structural isomers of the bicyclic ring system containing a pyrrole moiety fused to a pyridine nucleus. The broad spectrum of pharmacological properties of pyrrolo[3,4-c]pyridine derivatives is the main reason for developing new compounds containing this scaffold. This review presents studies on the biological activity of pyrrolo[3,4-c]pyridines that have been reported in the scientific literature. Most of these derivatives have been studied as analgesic and sedative agents. Biological investigations have shown that pyrrolo[3,4-c]pyridines can be used to treat diseases of the nervous and immune systems. Their antidiabetic, antimycobacterial, antiviral, and antitumor activities also have been found.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/eb2ac6eadf414133ab46b4e9ec5b490a Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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