Effects of red blood cell transfusion on patients undergoing cardiac surgery in Queensland – a retrospective cohort study

Autor: Nchafatso. G. Obonyo, Vikash Dhanapathy, Nicole White, Declan P. Sela, Reema H. Rachakonda, Matthew Tunbridge, Beatrice Sim, Derek Teo, Zohaib Nadeem, Louise E. See Hoe, Gianluigi Li Bassi, Jonathon P. Fanning, John-Paul Tung, Jacky Y. Suen, John F. Fraser
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-9 (2024)
Druh dokumentu: article
ISSN: 1749-8090
DOI: 10.1186/s13019-024-02974-7
Popis: Abstract Background Packed red blood cell (pRBC) transfusion is a relatively safe and mainstay treatment commonly used in cardiac surgical patients. However, there is limited evidence on clinical effects of transfusing blood nearing end-of shelf life that has undergone biochemical changes during storage. Objective To investigate evidence of associations between morbidity/mortality and transfusion of blood near end of shelf-life (> 35 days) in cardiac surgical patients. Methods Data from the Queensland Health Admitted Patient Data Collection database 2007–2013 was retrospectively analysed. Coronary artery bypass graft and valvular repair patients were included. Multivariable logistic regression was used to examine the effect of pRBC age ( 4) were supported.
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