Phytochemical and biological studies of Carduus pycnocephalus L.

Autor: Latifa A. Al-Shammari, Wafaa H.B. Hassan, Hanan M. Al-Youssef
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Saudi Chemical Society, Vol 19, Iss 4, Pp 410-416 (2015)
Druh dokumentu: article
ISSN: 1319-6103
DOI: 10.1016/j.jscs.2012.05.002
Popis: Seven flavonoidal compounds, apigenin (1), kaempferol-3-O-β-d-glucoside (2), kaempferol-3-O-α-l-rhamnoside (3), kaempferol-7-methoxy-3-O-α-l-rhamnoside (4), diosmetin-7-O-β-d-xylosyl-(1‴→6″)-β-d-glucopyranoside (5), diosmetin-7-O-α-l-arabinosyl (1‴→6″)-β-d-glucopyranoside (6), kaempferol-3-O-α-l-rhamnosyl-(1‴→2″)-α-l-rhamnoside (7), in addition to lupeol (8), β-sitosterol (9) and β-sitosterol-3-O-β-d-glucoside (10) were isolated from the aerial parts of Carduus pycnocephalus L. The structures of the isolated compounds were established by UV, IR, FAB-MS, ESI-MS, EI-MS, 1D and 2D NMR spectroscopic methods. Compounds 1, 2, and 4 were reported for the first time from C. pycnocephalus and compounds 5 and 7 were first reported from the genus Carduus. Anti-inflammatory, antispasmodic and hypotensive activities were assessed for all extracts which showed variable activities.
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