Aquaporins in Urinary Extracellular Vesicles (Exosomes)

Autor: Sayaka Oshikawa, Hiroko Sonoda, Masahiro Ikeda
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: International Journal of Molecular Sciences, Vol 17, Iss 6, p 957 (2016)
Druh dokumentu: article
ISSN: 1422-0067
DOI: 10.3390/ijms17060957
Popis: Since the successful characterization of urinary extracellular vesicles (uEVs) by Knepper’s group in 2004, these vesicles have been a focus of intense basic and translational research worldwide, with the aim of developing novel biomarkers and therapeutics for renal disease. Along with these studies, there is growing evidence that aquaporins (AQPs), water channel proteins, in uEVs have the potential to be diagnostically useful. In this review, we highlight current knowledge of AQPs in uEVs from their discovery to clinical application.
Databáze: Directory of Open Access Journals