Determination of prooxidant-antioxidant balance during uncomplicated pregnancy using a rapid assay
| Autor: | Boskabadi Hassan, Moeini Mahdieh, Tara Fatemeh, Tavallaie Shima, Saber Hamidreza, Nejati Raheleh, Hosseini Golkoo, Mostafavi-Toroghi Hesam, Ferns Gordon A.A., Ghayour-Mobarhan Majid |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Journal of Medical Biochemistry, Vol 32, Iss 3, Pp 227-232 (2013) |
| Druh dokumentu: | article |
| ISSN: | 1452-8258 1452-8266 |
| Popis: | Background: Oxidative stress is thought to be a major contributor to complications during pregnancy, for example preeclampsia. However, reports regarding prooxidant-antioxidant balance in uncomplicated pregnancy are inconsistent. In this study, we aimed to compare the levels of oxidative stress in non-pregnant women with apparently normal pregnant women during the first trimester and at delivery. Methods: An assay for the determination of prooxidant-antioxidant balance (PAB) was used in this study, in which the prooxidant burden and the antioxidant capacity were measured simultaneously in a single assay. The levels of oxidative stress were determined in 85 non-pregnant and 64 primigravid pregnant women. Results: Demographic data and biochemical indices did not differ significantly between the groups. Differences between PAB values were significant based on one-way ANOVA analysis (P |
| Databáze: | Directory of Open Access Journals |
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