A fatal case of hepatitis B virus (HBV) reactivation during long-term, very-low-dose steroid treatment in an inactive HBV carrier

Autor:	Joong Ho Bae, Joo Hyun Sohn, Hye Soon Lee, Hye Sun Park, Yil Sik Hyun, Tae Yeob Kim, Chang Soo Eun, Yong Cheol Jeon, Dong Soo Han
Jazyk:	angličtina
Rok vydání:	2012
Předmět:	Hepatitis B virus Liver failure Steroids Virus activation Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Clinical and Molecular Hepatology, Vol 18, Iss 2, Pp 225-228 (2012)
Druh dokumentu:	article
ISSN:	2287-2728 2287-285X
DOI:	10.3350/cmh.2012.18.2.225
Popis:	Hepatitis B virus (HBV) may be reactivated after chemotherapy or immunosuppressive therapy, and therefore administration of antiviral agents before such treatment is recommended. Most reported cases of reactivation are associated with high doses of immunosuppressive agents or combination therapy. We present a case of a previously inactive HBV carrier with an acute severe flare-up during a long-term, very-low-dose (2.5 mg/day) steroid treatment for rheumatoid arthritis. We suggest that even a minimal dose of single-regimen oral steroid can cause reactivation of indolent, inactive HBV.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/b27002148033424dbe675f700097ea01 Zobrazit plný text záznamu View record in DOAJ