| Autor: |
Javier Arellano, Carolina Carrasco, Carolina García |
| Jazyk: |
English<br />Spanish; Castilian |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Medwave, Vol 20, Iss 10, Pp e8053-e8053 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
0717-6384 |
| DOI: |
10.5867/medwave.2020.10.8053 |
| Popis: |
Alopecia areata is a common type of non-scarring alo¬pecia. Although the exact pathogenesis remains elusive, alopecia areata is thought to have a multifactorial etiology described as an interplay of genetic predisposition and environmental exposures. In patients with genetic susceptibility, stress, infection, and microtrauma have been documented to decrease immunosuppressive cytokines that generally maintain the hair follicle's immune privilege. There is currently no curative therapy for alopecia areata, although some treatments can induce hair growth in a percentage of patients. It has been postulated that simvastatin reestablishes the immune privilege, and ezetimibe would provide an immunomodulatory and anti-inflammatory effect. We report a case of a 23 years-old woman with alopecia areata successfully treated with simvastatin/ezetimibe. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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