Postural and intention tremors: Detailed clinical study of essential tremor vs. Parkinson’s disease

Autor: Eliezer J Sternberg, Roy N Alcalay, Oren A Levy, Elan D Louis
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Frontiers in Neurology, Vol 4 (2013)
Druh dokumentu: article
ISSN: 1664-2295
DOI: 10.3389/fneur.2013.00051
Popis: ABSTRACTBackground: An estimated 30-50% of essential tremor diagnoses are incorrect, and the true diagnosis in those patients is often Parkinson’s disease or other tremor disorders. There are general statements about the tremor in these essential tremor and Parkinson’s disease, but published data on the more subtle characteristics of tremor are surprisingly limited. Postural tremor may occur in both disorders, adding to the difficulty. There are several anecdotal impressions regarding specific features of postural tremor in essential tremor vs. Parkinson’s disease, including joint distribution (e.g., phalanges, metacarpal-phalangeal joints, wrist), tremor directionality (e.g., flexion-extension vs. pronation-supination), and presence of intention tremor. However, there is little data to support these impressions.Methods: In this cross-sectional study, 100 patients (essential tremor, 50 Parkinson’s disease) underwent detailed videotaped neurological examinations. Arm tremor was rated by a movement disorder neurologist who assessed severity and directionality across multiple joints. Results: During sustained arm extension, essential tremor patients exhibited more wrist than metacarpal-phalangeal and phalangeal joint tremor than did Parkinson’s disease patients (p
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