Editors’ Choice—Challenges and Opportunities for Developing Electrochemical Biosensors with Commercialization Potential in the Point-of-Care Diagnostics Market

Autor: Amir Ali Akhlaghi, Harmanjit Kaur, Bal Ram Adhikari, Leyla Soleymani
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: ECS Sensors Plus, Vol 3, Iss 1, p 011601 (2024)
Druh dokumentu: article
ISSN: 2754-2726
DOI: 10.1149/2754-2726/ad304a
Popis: There is a plethora of electrochemical biosensors developed for ultrasensitive detection of clinically relevant biomarkers. However, many of these systems lose their performance in heterogeneous clinical samples and are too complex to be operated by end users at the point-of-care (POC), prohibiting their commercial success. Integration of biosensors with sample processing technology addresses both of these challenges; however, it adds to the manufacturing complexity and the overall cost of these systems. Herein, we review the different components of a biosensor and avenues for creating fully integrated systems. In the context of integration, we focus on discussing the trade-offs between sensing performance, cost, and scalable manufacturing to guide the readers toward designing new electrochemical biosensors with commercialization potential.
Databáze: Directory of Open Access Journals