Schistosoma mansoni granulomas in the skeletal striated muscles in the murine model of neuroschistosomiasis: histological findings

Autor: Thiago Andre Alves Fidelis, Geraldo Brasileiro-Filho, Patricia M Parreiras, Paulo Marcos Z Coelho, Neusa Araujo, Marco Vinicius Chaud, Denicezar Angelo Baldo, Nelson Brancaccio dos Santos, José Roberto Lambertucci
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Memorias do Instituto Oswaldo Cruz, Vol 115 (2020)
Druh dokumentu: article
ISSN: 1678-8060
0074-0276
DOI: 10.1590/0074-02760190383
Popis: Schistosomiasis mansoni presents many clinical manifestations during migration of schistosomes in their hosts, including diarrhea, hepatomegaly, splenomegaly, liver abscesses, skinlesions, brain tumors and myeloradiculopathy. No lesions have been reported in skeletal striated muscles due to schistosomiasis mansoni in the literature. This short communication reports the histopathological findings on skeletal musculature in a murine model of neuroeschistosomiasis mansoni. Lesions were found in the tongue, masseter muscle, buccinator muscle, digastric muscle and temporalis muscle. Worm recovery was carried out to confirm the infection. We describe here, for the first time in the literature, injuries in the skeletal musculature due to Schistosoma mansoni nfection.
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