| Autor: |
Biljana R. Dekić, Niko S. Radulović, Vidoslav S. Dekić, Rastko D. Vukićević, Radosav M. Palić |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Molecules, Vol 15, Iss 4, Pp 2246-2256 (2010) |
| Druh dokumentu: |
article |
| ISSN: |
1420-3049 |
| DOI: |
10.3390/molecules15042246 |
| Popis: |
Synthesis, spectral analysis and bioactivity of new coumarin derivatives are described in this paper. Eight new coumarin derivatives were synthesized in moderate to good yields by condensation of 4-chloro-3-nitrocoumarin and the corresponding heteroarylamine. The synthesized compounds were tested for their in vitro antimicrobial activity, in a standard disk diffusion assay, against thirteen strains of bacteria and three fungal strains. They have shown a wide range of activity - from one completely inactive compound to medium active ones. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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