Autor: |
Chelsea Iwamoto, Kelsey E. Lesteberg, Molly M. Lamb, Diva M. Calvimontes, Kejun Guo, Bradley S. Barrett, Kaylee L. Mickens, Lindsey M. Duca, Jose Monzon, Anna N. Chard, Gerber Guzman, Edgar Barrios, Neudy Rojop, Kareen Arias, Melissa Gomez, Claudia Paiz, Guillermo Antonio Bolanos, Kathryn M. Edwards, Emily Zielinski Gutierrez, Eduardo Azziz-Baumgartner, Edwin J. Asturias, Mario L. Santiago, J. David Beckham, Daniel Olson |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
Vaccines, Vol 10, Iss 7, p 1160 (2022) |
Druh dokumentu: |
article |
ISSN: |
2076-393X |
DOI: |
10.3390/vaccines10071160 |
Popis: |
Essential agricultural workers work under occupational conditions that may increase the risk of SARS-CoV-2 exposure and transmission. Data from an agricultural worker cohort in Guatemala, and anti-SARS-CoV-2 nucleocapsid IgG (anti-N IgG) testing were used to estimate past infections and analyze risk factors associated with seropositivity at enrollment and association with SARS-CoV-2 infection. The stability of neutralizing antibody (NAb) responses were assessed in a subset of participants. The adjusted relative risk (aRR) for seroprevalence at enrollment was estimated accounting for correlations within worksites. At enrollment, 616 (46.2%) of 1334 (93.2%) participants had anti-N IgG results indicating prior SARS-CoV-2 infection. A cough ≤ 10 days prior to enrollment (aRR = 1.28, 95% CI: 1.13–1.46) and working as a packer (aRR = 2.00, 95% CI: 1.67–2.38) or packing manager within the plants (aRR = 1.82, 95% CI: 1.36–2.43) were associated with increased risk of seropositivity. COVID-19 incidence density among seronegative workers was 2.3/100 Person-Years (P-Y), higher than seropositive workers (0.4/100 P-Y). Most workers with follow-up NAb testing (65/77, 84%) exhibited a 95% average decrease in NAb titers in |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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