| Autor: |
Xiangyu Liu, Zhengping Shao, Wenxia Jiang, Brian J. Lee, Shan Zha |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/ncomms13816 |
| Popis: |
Non-homologous end-joining is the key pathway for repairing double-stranded DNA breaks in mammalian cells. Here the authors show that PAXX promotes the accumulation of KU at DNA breaks and is essential for end-joining in cells lacking XLF. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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