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Fabrizio Spada, Tanya M Barnes, Kerryn A Greive Research & Development, Ego Pharmaceuticals, Braeside, Victoria, AustraliaCorrespondence: Fabrizio SpadaEgo Pharmaceuticals Pty Ltd, 21-31 Malcolm Road, Braeside, Victoria 3195, AustraliaTel +61 39 586 8874Fax +61 39 580 7647Email fabrizio.spada@egopharm.comBackground: Increased skin colonization by Staphylococcus aureus is associated with atopic eczema (AE) severity. Reduction of S. aureus levels on the skin results in an improvement in the clinical condition.Methods: The antimicrobial activity of topical products including a bath oil, cream, and wash combining antiseptics and emollients (A+E) was compared to products containing emollients only. The preference of patients with AE for A+E cream or emollient only cream to relieve symptoms of itching, erythema, and inflammation when applied three times daily for 10 days is evaluated. Repeat insult patch testing of the products is also conducted.Results: A significant reduction in microbial counts was found following use of A+E bath oil (4.09±0.32 vs 6.20±0.24 log10 cfu/mL S. aureus, P |
