The combined value of mpUS and mpMRI-TRUS fusion for the diagnosis of clinically significant prostate cancer

Autor: Xin Zhang, Hua Hong, Danyan Liang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Cancer Imaging, Vol 22, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 1470-7330
DOI: 10.1186/s40644-022-00498-8
Popis: Abstract Objective To evaluate the combined efficacy of multiparametric ultrasonography (mpUS) and multiparametric magnetic resonance imaging/transrectal ultrasound (mpMRI-TRUS) fusion for detecting clinically significant prostate cancer (csPCa). Methods From November 2019 to September 2021, biopsy-naïve patients underwent mpMRI-TRUS fusion imaging combined with mpUS-guided targeted biopsies (TB) and systematic biopsies (SB). To further evaluate the additional diagnostic value of mpUS, the imaging features of 202 focus obtained from fusion imaging were assessed. The diagnostic accuracies of mpMRI-TRUS fusion imaging and the combination of mpMRI-TRUS fusion imaging with mpUS for csPCa were comparatively evaluated. Results A total of 202 prostate lesions (160 patients) were included in the final analysis, of which 105 were csPCa, 16 were ciPCa, and 81 were noncancerous. The median patient age was 69 (65–73) years and the median tPSA was 22.07 (11.22–62.80) ng/mL. For csPCa, the detection rate of TB was higher than that of SB (50.0% vs. 45.5%, p
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