Reversibilidad mandibular de la rigidez cadavérica por medios químicos en un modelo de rata

Autor: Jairo Alfonso Tovar-Franco, Diana Constanza Aparicio-Castellanos, Luisa Fernanda Henriquez Higuera
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2009
Předmět:
Zdroj: Universitas Scientiarum, Vol 14, Iss 1, Pp 58-70 (2009)
Druh dokumentu: article
ISSN: 0122-7483
2027-1352
Popis: Mandibular reversibility of the cadaverous stiffness by chemical means in a rat model. The main problem that a dentist faces when collectingpostmortem evidence is the buccal opening, which is limited by the cadaverous stiffness phenomenon that begins 3 hours after death. Thisphenomenon persists until it is destroyed by the late autolytic processes of decomposition, after 36 hours postmortem. Objective. To analyzethe feasibility of accelerating the reversion of the mandibular cadaverous stiffness by means of chemical substances to facilitate the buccalopening. Materials and methods. We assessed substances capable of altering the pH, chelating intramuscular calcium or inducing proteolysisof the actin-myosin complex of the masticatory muscles with cadaverous stiffness in Wistar rats. Results. We found that mandibularcadaverous stiffness in Wistar rats appears after 2.5 hours of death. After 3.5 hours, once the rigidity was established, we carried outinfiltrations with EDTA (20 mM), NaHCO3 (50 μM), Na2CO3 (50 μM) and papain (10 μM). NaHCO3 and Na2CO3 solutions significantlyincreased (p
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