A survey on hematology-oncology pediatric AIEOP centers: prophylaxis, empirical therapy and nursing prevention procedures of infectious complications
| Autor: | Susanna Livadiotti, Giuseppe Maria Milano, Annalisa Serra, Laura Folgori, Alessandro Jenkner, Elio Castagnola, Simone Cesaro, Mario R. Rossi, Angelica Barone, Giulio Zanazzo, Francesca Nesi, Maria Licciardello, Raffaella De Santis, Ottavio Ziino, Monica Cellini, Fulvio Porta, Desiree Caselli, Giuseppe Pontrelli |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Haematologica, Vol 97, Iss 1 (2012) |
| Druh dokumentu: | article |
| ISSN: | 0390-6078 1592-8721 |
| DOI: | 10.3324/haematol.2011.048918 |
| Popis: | A nationwide questionnaire-based survey was designed to evaluate the management and prophylaxis of febrile neutropenia in pediatric patients admitted to hematology-oncology and hematopoietic stem cell transplant units. Of the 34 participating centers, 40 and 63%, respectively, continue to prescribe antibacterial and antimycotic prophylaxis in low-risk subjects and 78 and 94% in transplant patients. Approximately half of the centers prescribe a combination antibiotic regimen as first-line therapy in low-risk patients and up to 81% in high-risk patients. When initial empirical therapy fails after seven days, 63% of the centers add empirical antimycotic therapy in low-and 81% in high-risk patients. Overall management varies significantly across centers. Preventive nursing procedures are in accordance with international guidelines. This survey is the first to focus on prescribing practices in children with cancer and could help to implement practice guidelines. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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