A nation-wide twin study of social cognition in schizophrenia spectrum disorders

Autor: Cecilie K. Lemvigh, Birte Y. Glenthøj, Birgitte Fagerlund
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: npj Schizophrenia, Vol 8, Iss 1, Pp 1-5 (2022)
Druh dokumentu: article
ISSN: 2334-265X
DOI: 10.1038/s41537-022-00223-1
Popis: Abstract We examined social cognition in 32 monozygotic (MZ) and 21 dizygotic (DZ) twin pairs concordant or discordant for a schizophrenia spectrum diagnosis and healthy control (HC) twin pairs (29 MZ/20 DZ). All participants were recruited through the Danish registers. Patients showed several deficits in the ability to detect sarcasm. Impairments were also observed in the unaffected MZ co-twins, indicating that social cognitive deficits could be a genetic vulnerability indicator of the disease. Worse social cognition was associated with lower intelligence and higher levels of psychopathology in patients.
Databáze: Directory of Open Access Journals