Severity of hyperechoic pancreas on ultrasonography as a risk factor for glycemic progression

Autor: Jiyun Oh, Hyun Jeong Park, Eun Sun Lee, Sung Bin Park, Byung Ihn Choi, Soohyun Ahn
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Ultrasonography, Vol 40, Iss 4, Pp 499-511 (2021)
Druh dokumentu: article
ISSN: 2288-5919
2288-5943
DOI: 10.14366/usg.20122
Popis: Purpose The aim of this study was to evaluate the association between the severity of hyperechoic pancreas (HP) on ultrasonography (US) and glycemic progression. Methods In total, 1,386 participants who underwent abdominal US as part of health examinations between December 2008 and May 2014 were included in this retrospective study. We classified pancreatic echogenicity on a 4-point scale, and compared it using two distinct criteria: fatty pancreas (FP) 1 criterion (normal vs. ≥mild HP) and FP2 criterion (normal/mild HP vs. ≥moderate HP). According to the presence of nonalcoholic fatty liver disease (NAFLD), participants were subdivided into four groups: non-NAFLD and non-HP, isolated NAFLD, isolated HP, and HP with NAFLD. Glycemic progression was defined as progression from normoglycemia to prediabetes or diabetes or progression from prediabetes to diabetes. Results During the follow-up (median, 5.9 years), 262 of the 1,386 participants developed glycemic progression. Using FP2, the probability of glycemic progression across the four subgroups showed cumulative aggravation for NAFLD and HP (all P
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