Plasmacytoid urothelial carcinoma with duodenal metastasis—A rare tumor with unusual site of metastasis with grim outcome

Autor: Aparna Chenniappan, Norton S Stephen, Bheemanathi H Srinivas, Sreerag K Sreenivasan, Ramkumar Govindarajalou
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Indian Journal of Pathology and Microbiology, Vol 67, Iss 1, Pp 175-177 (2024)
Druh dokumentu: article
ISSN: 0377-4929
0974-5130
DOI: 10.4103/ijpm.ijpm_840_21
Popis: Plasmacytoid urothelial carcinoma (PUC) is a newly recognized rare variant of urothelial carcinoma, which is now being increasingly diagnosed prospectively as well as by retrospective analysis of cases with a poor prognosis. Morphologically, these tumors simulate plasma cell neoplasms and pose a diagnostic challenge. Identifying this variant is essential in two aspects: therapy and prognosis. Here, we present a case who underwent multiple transurethral resection of bladder tumor (TURBT) procedures, each with a diagnosis of urothelial carcinoma, the plasmacytoid type which was confirmed on radical cystectomy, and after 1 year, the patient presented with duodenal metastasis. We discuss the morphological aspects of differentiating this tumor from variants of urothelial carcinoma and other tumors with a plasmacytoid appearance. Despite the recognition and aggressive treatment, the patient expires within 2 years of the first diagnosis of bladder carcinoma.
Databáze: Directory of Open Access Journals
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