Use of gammaglobulin in transplantation of hematopoletic stem cellas and in kidney transplant

Autor: Ruíz Morales Jorge Alberto, Shanat Cruz-Medina Cinthya, Pérez García Martín
Jazyk: Spanish; Castilian
Rok vydání: 2014
Předmět:
Zdroj: Acta Pediátrica de México, Vol 34, Iss 6, Pp 348-352 (2014)
Druh dokumentu: article
ISSN: 0186-2391
2395-8235
DOI: 10.18233/APM34No6pp348-352
Popis: Intravenous immunoglobulin (IVIG) preparation comprise a pooled IgG antiboidies from the serum of thousands of donors and has been used as therapy in several pathologies such as: primary im- munodeficiency’s, autoimmune diseases, Kawasaki disease and on transplantation field to treat graft versus host disease, viral infec- tions and sensitization due to anti-donor antibodies. The anti-donor antibodies are an important risk factor for acute humoral rejections on kidney transplantation and are a very important risk factor for graft failure after hematopoietic stem cell transplantation. Using IVIG to treat patients with anti-donor antibodies might reduced the risk of acute kidney rejection and graft failure following hematopoietic stem cell transplantation.
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