Evaluation of the outcomes in patients with chronic myeloid leukemia treated with imatinib in 18-year follow-up

Autor: Mozafar Aznab, Ali Shahriari-Ahmadi, Fatemeh Heydarpour
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Leukemia Research Reports, Vol 16, Iss , Pp 100271- (2021)
Druh dokumentu: article
ISSN: 2213-0489
DOI: 10.1016/j.lrr.2021.100271
Popis: The objective of this paper is to examine the effects of Imatinib on patients who are at the chronic phase of chronic myeloid leukemia (CML). Method: Totally, 79 patients with CML who received the treatment between 2003 and 2020 entered the study. The patients were evaluated in terms of molecular response rate and overall survival (OS). Results: About 75.9% of patients achieved deep molecular response in mean follow-up of 89.92 months. The OS rate was about 91.2%. Conclusion: There was no considerable cumulative toxicity with Imatinib long-term use. A high percent of patients had a deep molecular response.
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