Effect of tramadol as a local anesthetic adjuvant in epidural labor analgesia: Randomized controlled study

Autor: Radwa Fathy Mansour, Mohamed Elsayed Afandy
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Egyptian Journal of Anaesthesia, Vol 37, Iss 1, Pp 1-8 (2021)
Druh dokumentu: article
ISSN: 11101849
1110-1849
DOI: 10.1080/11101849.2020.1862986
Popis: ABSTRACTBackground: Epidural analgesia has been established to be the best modality for painless labor. This study hypothesized to evaluate the effect of adding tramadol as an adjuvant to bupivacaine in epidural labor analgesia.Methods: Sixty parturients were allocated into two equal groups. Group B received a total volume of 10 ml bupivacaine 0.25% in normal saline. Group BT received a total volume of 10 ml bupivacaine 0.25% plus tramadol 5 mg/ml in normal saline as a loading dose, followed by continuous infusion of bupivacaine 0.125% at rate 10 ml/h 15 min after a loading dose for both groups. The onset of analgesia, degree of motor block, sedative effect, hemodynamic parameters, visual analogue scale (VAS), number of top-up doses, fetal outcomes, any related side effects, and maternal satisfaction were recorded.Results: Faster onset of analgesia was achieved in BT group compared to B group (7.9 ± 2.68 vs 15.3 ± 3.3, respectively: P
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