Interleukin-1 Modulation of Human Placental Trophoblast Proliferation
| Autor: | Athip Nilkaeo, Suthinee Bhuvanath |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: | |
| Zdroj: | Mediators of Inflammation, Vol 2006 (2006) |
| Druh dokumentu: | article |
| ISSN: | 0962-9351 1466-1861 |
| DOI: | 10.1155/MI/2006/79359 |
| Popis: | During early pregnancy, interleukin-1 (IL-1) is mainly produced and secreted by maternal decidua. Yet, its biological function on placental cells is not well defined. In this study, we employed JAR choriocarcinoma cell line as a model of human placental trophoblast to study the effect of IL-1. Treatment with recombinant human IL-1β resulted in significant inhibition of JAR proliferation (P |
| Databáze: | Directory of Open Access Journals |
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