Chronic pain, depression and cognitive impairment: a close relationship

Autor: N. V. Latysheva, E. G. Filatova, D. V. Osipova
Jazyk: ruština
Rok vydání: 2018
Předmět:
Zdroj: Нервно-мышечные болезни, Vol 8, Iss 3, Pp 34-42 (2018)
Druh dokumentu: article
ISSN: 2222-8721
2413-0443
DOI: 10.17650/2222-8721-2018-8-3-34-42
Popis: Over a half of chronic pain (CP) patients present with cognitive complaints, which increase their disability and impact quality of life. The paper reviews objective impairments in memory, attention, processing speed and executive function demonstrated in the CP population. The paper also reviews common pathology underlying cognitive impairment and CP: neuroplasticity in the shared brain areas, neurotransmitter and other molecular mechanisms. Common mechanisms in CP and depression precipitating cognitive impairment are also discussed. The paper also compares the potential of different antidepressants to improve cognitive functions in depression and CP.
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