Antimicrobial properties and dental pulp stem cell cytotoxicity using carboxymethyl cellulose-silver nanoparticles deposited on titanium plates
| Autor: | Martha Alicia Laredo-Naranjo, Roberto Carrillo-Gonzalez, Myriam Angelica De La Garza-Ramos, Marco Antonio Garza-Navarro, Hilda H. H. Torre-Martinez, Casiano Del Angel-Mosqueda, Roberto Mercado-Hernandez, Roberto Carrillo-Fuentevilla |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Acta Biomaterialia Odontologica Scandinavica, Vol 2, Iss 1, Pp 60-67 (2016) |
| Druh dokumentu: | article |
| ISSN: | 2333-7931 23337931 |
| DOI: | 10.3109/23337931.2016.1160783 |
| Popis: | Objective: To evaluate the antimicrobial properties and dental pulp stem cells (DPSCs) cytotoxicity of synthesized carboxymethyl cellulose-silver nanoparticles impregnated on titanium plates. Material and methods: The antibacterial effect of silver nanoparticles in a carboxymethyl cellulose matrix impregnated on titanium plates (Ti-AgNPs) in three concentrations: 16%, 50% and 100% was determined by adding these to bacterial cultures of Streptococcus mutans and Porphyromonas gingivalis. The Ti-AgNPs cytotoxicity on DPSCs was determined using a fluorimetric cytotoxicity assay with 0.12% chlorhexidine as a positive control. Results: Silver nanoparticles in all concentrations were antimicrobial, with concentrations of 50% and 100% being more cytotoxic with 4% cell viability. Silver nanoparticles 16% had a cell viability of 95%, being less cytotoxic than 0.12% chlorhexidine. Conclusions: Silver nanoparticles are a promising structure because of their antimicrobial properties. These have high cell viability at a concentration of 16%, and are less toxic than chlorhexidine. |
| Databáze: | Directory of Open Access Journals |
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