Iron-Uptake Systems of Chicken-Associated Salmonella Serovars and Their Role in Colonizing the Avian Host

Autor: Dinesh H. Wellawa, Brenda Allan, Aaron P. White, Wolfgang Köster
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Microorganisms, Vol 8, Iss 8, p 1203 (2020)
Druh dokumentu: article
ISSN: 2076-2607
DOI: 10.3390/microorganisms8081203
Popis: Iron is an essential micronutrient for most bacteria. Salmonella enterica strains, representing human and animal pathogens, have adopted several mechanisms to sequester iron from the environment depending on availability and source. Chickens act as a major reservoir for Salmonella enterica strains which can lead to outbreaks of human salmonellosis. In this review article we summarize the current understanding of the contribution of iron-uptake systems to the virulence of non-typhoidal S. enterica strains in colonizing chickens. We aim to address the gap in knowledge in this field, to help understand and define the interactions between S. enterica and these important hosts, in comparison to mammalian models.
Databáze: Directory of Open Access Journals