| Autor: |
Phillip H. Hwang, W.T. Longstreth Jr, Willa D. Brenowitz, Stephen M. Thielke, Oscar L. Lopez, Courtney E. Francis, Steven T. DeKosky, Annette L. Fitzpatrick |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2352-8729 |
| DOI: |
10.1002/dad2.12054 |
| Popis: |
Abstract Introduction Hearing and vision loss are independently associated with dementia, but the impact of dual sensory impairment (DSI) on dementia risk is not well understood. Methods Self‐reported measures of hearing and vision were taken from 2051 participants at baseline from the Gingko Evaluation of Memory Study. Dementia status was ascertained using standardized criteria. Cox models were used to estimate risk of dementia associated with number of sensory impairments (none, one, or two). Results DSI was significantly associated with higher risk of all‐cause dementia (hazard ratio [HR] = 1.86; 95% confidence interval [CI] = 1.25‐2.76) and Alzheimer's disease (HR = 2.12; 95% CI = 1.34‐3.36). Individually only visual impairment was independently associated with an increased risk of all‐cause dementia (HR = 1.32; 95% CI = 1.02‐1.71). Discussion Older adults with DSI are at a significantly increased risk for dementia. Further studies are needed to evaluate whether treatments can modify this risk. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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