Proteomic change in the upper lobe of the left lung of Beagle dogs at the lung migration stage of Toxocara canis infection

Autor: Wen-Bin Zheng, Hui-Jie Qiu, Han-Dan Xiao, Yang Zou, Xing-Quan Zhu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Parasites & Vectors, Vol 17, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 1756-3305
DOI: 10.1186/s13071-024-06302-9
Popis: Abstract Background Toxocara canis is considered one of the most neglected parasitic zoonoses and threatens the health of millions of people worldwide with a predilection for pediatric and adolescent populations in impoverished communities. Exploring the invasion and developmental mechanisms associated with T. canis infection in its definitive canine hosts will help to better control zoonotic toxocariasis. Methods Proteomic changes in samples from the upper lobe of the left lung of Beagle puppies were systematically analyzed by quantitative proteomic technology of data-independent acquisition (DIA) at 96 h post-infection (hpi) with T. canis. Proteins with P-values 1.5 or
Databáze: Directory of Open Access Journals
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