| Autor: |
David W Chan, Winnie W Y Hui, Patty C H Cai, Michelle X Liu, Mingo M H Yung, Celia S L Mak, Thomas H Y Leung, Karen K L Chan, Hextan Y S Ngan |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Předmět: |
|
| Zdroj: |
PLoS ONE, Vol 7, Iss 12, p e52578 (2012) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0052578 |
| Popis: |
Ovarian cancer is a highly lethal disease with poor prognosis and especially in high-grade tumor. Emerging evidence has reported that aberrant upregulation and activation of GRB7, ERK as well as FOXM1 are closely associated with aggresivenesss of human cancers. However, the interplay between these factors in the pathogenesis of human cancers still remains unclear. In this study, we found that GRB7 (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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