Emergence of Candida auris in Brazil in a COVID-19 Intensive Care Unit

Autor: João N. de Almeida, Elaine C. Francisco, Ferry Hagen, Igor B. Brandão, Felicidade M. Pereira, Pedro H. Presta Dias, Magda M. de Miranda Costa, Regiane T. de Souza Jordão, Theun de Groot, Arnaldo L. Colombo
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Fungi, Vol 7, Iss 3, p 220 (2021)
Druh dokumentu: article
ISSN: 2309-608X
DOI: 10.3390/jof7030220
Popis: In December 2020, Candida auris emerged in Brazil in the city of Salvador. The first two C. auris colonized patients were in the same COVID-19 intensive care unit. Antifungal susceptibility testing showed low minimal inhibitory concentrations of 1 µg/mL, 2 µg/mL, 0.03 µg/L, and 0.06 µg/mL for amphotericin B, fluconazole, voriconazole, and anidulafungin, respectively. Microsatellite typing revealed that the strains are clonal and belong to the South Asian clade C. auris. The travel restrictions during the COVID-19 pandemic and the absence of travel history among the colonized patients lead to the hypothesis that this species was introduced several months before the recognition of the first case and/or emerged locally in the coastline Salvador area.
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